内容简介
本综述论文聚焦用于力学生物学研究装备，分析了其科研、市场现状，并探讨了其可能的未来发展方向。各种研究和技术领域的重大进步促成了对人体生理动力学的显著发现。为了更准确地模拟复杂的生理环境，研究已从二维（2D）培养系统转向更复杂的三维（3D）动态培养。与生物反应器或基于微流体的培养模型不同，细胞通常接种在聚合物基质上或载入3D打印结构中，并对这些结构施加机械刺激以研究细胞对机械应力（例如拉伸或压缩）的反应。本综述侧重于目前市场上可用的或由研究团队定制或受专利保护的机械刺激装置的工作原理，并强调了仍有待改进的主要功能。这些功能可以用于在未来进行更可靠和准确的机械生物学研究。
文章导读
图1 细胞培养模型可以处于静态或动态模式
图2 用于力学生物学研究的机械刺激装置示例
图3 使用市售设备的研究的细胞结果
图4 四种拉伸工作原理的表示
参考文献
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